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human wilms tumor cell lines g401  (ATCC)


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    ATCC human wilms tumor cell lines g401
    Human Wilms Tumor Cell Lines G401, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 244 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+wilms+tumor+cell+lines+g401/G-401/pm40483799-80-0-31
    Average 95 stars, based on 244 article reviews
    human wilms tumor cell lines g401 - by Bioz Stars, 2026-09
    95/100 stars

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    Wilms Tumor Assay:

    Article Title: Expression of the immune gene related to energy metabolism (NDRG1) in Wilms' tumor and its correlation with prognosis.
    Article Snippet: Background and objective: This study aimed to investigate the expression of NDRG1 in Wilms’ tumor and analyze its correlation with WT prognosis, thereby elucidating its role and potential mechanisms in the onset and pro-



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    95
    ATCC human wilms tumor cell lines g401
    Human Wilms Tumor Cell Lines G401, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+wilms+tumor+cell+lines+g401/G-401/pm40483799-80-0-31
    Average 95 stars, based on 1 article reviews
    human wilms tumor cell lines g401 - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    95
    ATCC g401 human kidney wilms tumor cell line
    SphK1 is highly expressed in SK-NEP-1 and <t>G401</t> cells. A. Western-blot analysis of SphK1 in eight cells. B. Cellular immunofluorescence analysis of SphK1 expression in <t>Wilms’</t> tumor cells. Results show that SphK1 is mostly expressed in the cell cytoplasm.
    G401 Human Kidney Wilms Tumor Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+wilms+tumor+cell+lines+g401/G-401/pmc05126303-104-2-12
    Average 95 stars, based on 1 article reviews
    g401 human kidney wilms tumor cell line - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

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    SphK1 is highly expressed in SK-NEP-1 and G401 cells. A. Western-blot analysis of SphK1 in eight cells. B. Cellular immunofluorescence analysis of SphK1 expression in Wilms’ tumor cells. Results show that SphK1 is mostly expressed in the cell cytoplasm.

    Journal: American Journal of Translational Research

    Article Title: A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms’ tumor cells in vitro and in vivo

    doi:

    Figure Lengend Snippet: SphK1 is highly expressed in SK-NEP-1 and G401 cells. A. Western-blot analysis of SphK1 in eight cells. B. Cellular immunofluorescence analysis of SphK1 expression in Wilms’ tumor cells. Results show that SphK1 is mostly expressed in the cell cytoplasm.

    Article Snippet: SK-NEP-1 and G401 Human kidney (Wilms’ Tumor) cell line obtained from the American Type Culture Collection (ATCC) was maintained in the MaCoy’s 5A (Life Technologies Inc., Gaithersburg, MD, USA) as introduced before [ 21 ].

    Techniques: Western Blot, Immunofluorescence, Expressing, Wilms Tumor Assay

    SKI-5C inhibits proliferations of SK-NEP-1 and G401 cells. A. Molecular structure of SKI-5C. B. Proliferation and IC50 analysis of SKI-5C. The IC50 of SKI-5C for SK-NEP-1 cells was about 4.11 uM. The IC50 of SKI-5C for G401 cells was about 9.74 uM. C. Micrographs of SK-NEP-1 and G401 cells treated with SKI-5C (2 uM and 5 uM) or DMSO. D. Proliferation analysis of SK-NEP-1 and G401 cells treated with 2 uM and 5 uM SKI-5C.

    Journal: American Journal of Translational Research

    Article Title: A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms’ tumor cells in vitro and in vivo

    doi:

    Figure Lengend Snippet: SKI-5C inhibits proliferations of SK-NEP-1 and G401 cells. A. Molecular structure of SKI-5C. B. Proliferation and IC50 analysis of SKI-5C. The IC50 of SKI-5C for SK-NEP-1 cells was about 4.11 uM. The IC50 of SKI-5C for G401 cells was about 9.74 uM. C. Micrographs of SK-NEP-1 and G401 cells treated with SKI-5C (2 uM and 5 uM) or DMSO. D. Proliferation analysis of SK-NEP-1 and G401 cells treated with 2 uM and 5 uM SKI-5C.

    Article Snippet: SK-NEP-1 and G401 Human kidney (Wilms’ Tumor) cell line obtained from the American Type Culture Collection (ATCC) was maintained in the MaCoy’s 5A (Life Technologies Inc., Gaithersburg, MD, USA) as introduced before [ 21 ].

    Techniques:

    Apoptosis analysis of SK-NEP-1 and G401 cells induced by SKI-5C. A. Annexin V staining of cells following 24 h treatment with SKI-5C at 2 uM or 5 uM compared with DMSO control treatment. B. The proportion of apoptotic cells in the SKI-5C-treated cells is significantly greater than that in the DMSO control group. C. Cell apoptosis analysis of SK-NEP-1 and G401 treated with 2 uM and 5 uM SKI-5C. D. Late cell apoptosis shows significant apoptosis in Wilms’ tumor cells.

    Journal: American Journal of Translational Research

    Article Title: A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms’ tumor cells in vitro and in vivo

    doi:

    Figure Lengend Snippet: Apoptosis analysis of SK-NEP-1 and G401 cells induced by SKI-5C. A. Annexin V staining of cells following 24 h treatment with SKI-5C at 2 uM or 5 uM compared with DMSO control treatment. B. The proportion of apoptotic cells in the SKI-5C-treated cells is significantly greater than that in the DMSO control group. C. Cell apoptosis analysis of SK-NEP-1 and G401 treated with 2 uM and 5 uM SKI-5C. D. Late cell apoptosis shows significant apoptosis in Wilms’ tumor cells.

    Article Snippet: SK-NEP-1 and G401 Human kidney (Wilms’ Tumor) cell line obtained from the American Type Culture Collection (ATCC) was maintained in the MaCoy’s 5A (Life Technologies Inc., Gaithersburg, MD, USA) as introduced before [ 21 ].

    Techniques: Staining, Control, Wilms Tumor Assay

    SKI-5C induces cell cycle disorder in SK-NEP-1 and G401 cells. A. Cell cycle analysis of SK-NEP-1 and G401 cells treated for 24 h with SKI-5C at 2 uM or 5 uM compared with DMSO control mock treatment. B. G2 phase in SK-NEP-1 (SKI-5C 5 uM group: 0.20% ± 0.01% vs. DMSO 7.96% ± 0.79%, respectively; P < 0.01); and G401 cells (SKI-5C 5 uM group: 0.10% ± 0.14% vs. DMSO 7.98% ± 0.82%, respectively; P < 0.01). C. Cell apoptosis and DNA fragmentation observed. D. Significant apoptosis is shown in SK-NEP-1 (SKI-5C 5 uM group: 16.83% ± 1.93% vs. DMSO 2.23% ± 0.90%, respectively; P < 0.01); and G401 cells (SKI-5C 5 uM group: 15.2% ± 1.95% vs. DMSO 3.23% ± 0.85%, respectively; P < 0.01).

    Journal: American Journal of Translational Research

    Article Title: A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms’ tumor cells in vitro and in vivo

    doi:

    Figure Lengend Snippet: SKI-5C induces cell cycle disorder in SK-NEP-1 and G401 cells. A. Cell cycle analysis of SK-NEP-1 and G401 cells treated for 24 h with SKI-5C at 2 uM or 5 uM compared with DMSO control mock treatment. B. G2 phase in SK-NEP-1 (SKI-5C 5 uM group: 0.20% ± 0.01% vs. DMSO 7.96% ± 0.79%, respectively; P < 0.01); and G401 cells (SKI-5C 5 uM group: 0.10% ± 0.14% vs. DMSO 7.98% ± 0.82%, respectively; P < 0.01). C. Cell apoptosis and DNA fragmentation observed. D. Significant apoptosis is shown in SK-NEP-1 (SKI-5C 5 uM group: 16.83% ± 1.93% vs. DMSO 2.23% ± 0.90%, respectively; P < 0.01); and G401 cells (SKI-5C 5 uM group: 15.2% ± 1.95% vs. DMSO 3.23% ± 0.85%, respectively; P < 0.01).

    Article Snippet: SK-NEP-1 and G401 Human kidney (Wilms’ Tumor) cell line obtained from the American Type Culture Collection (ATCC) was maintained in the MaCoy’s 5A (Life Technologies Inc., Gaithersburg, MD, USA) as introduced before [ 21 ].

    Techniques: Cell Cycle Assay, Control

    Micrographs showing TUNEL staining of cells treated with SKI-5C (2 uM and 5 uM) for 24 h. Red cells demonstrates the induction of DNA fragmentation. A. DNA fragmentation increases significantly with SKI-5C treatment compared with mock treatment in both SK-NEP-1 and G401 cells. B. Results show the percentages of TUNEL positive cells in SK-NEP-1 (SKI-5C 10 uM group: 56.5% ± 9.49% vs. DMSO 2.2% ± 1.99%, respectively; P < 0.01); and G401 cells (SKI-5C 10 uM group: 39.8% ± 8.13% vs. DMSO 2.4% ± 1.67%, respectively; P < 0.01). **P < 0.01.

    Journal: American Journal of Translational Research

    Article Title: A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms’ tumor cells in vitro and in vivo

    doi:

    Figure Lengend Snippet: Micrographs showing TUNEL staining of cells treated with SKI-5C (2 uM and 5 uM) for 24 h. Red cells demonstrates the induction of DNA fragmentation. A. DNA fragmentation increases significantly with SKI-5C treatment compared with mock treatment in both SK-NEP-1 and G401 cells. B. Results show the percentages of TUNEL positive cells in SK-NEP-1 (SKI-5C 10 uM group: 56.5% ± 9.49% vs. DMSO 2.2% ± 1.99%, respectively; P < 0.01); and G401 cells (SKI-5C 10 uM group: 39.8% ± 8.13% vs. DMSO 2.4% ± 1.67%, respectively; P < 0.01). **P < 0.01.

    Article Snippet: SK-NEP-1 and G401 Human kidney (Wilms’ Tumor) cell line obtained from the American Type Culture Collection (ATCC) was maintained in the MaCoy’s 5A (Life Technologies Inc., Gaithersburg, MD, USA) as introduced before [ 21 ].

    Techniques: TUNEL Assay, Staining